Lipids and Lipid Derivatives
Apexbio Technology LLC Dexamethasone acetate 1177-87-3 5g
Dexamethasone acetate a synthetic glucocorticoid acts by binding to glucocorticoid receptors influencing gene transcription to suppress inflammatory and immune responses By modulating cytokine production and inhibiting interleukin (IL) signaling pathways dexamethasone acetate serves as an interleukin receptor modulator Typically applied in research related to inflammation autoimmune diseases and cytokine-mediated cellular events it is extensively utilized in functional assays to understand receptor-ligand interactions signal transduction and therapeutic mechanisms Studies report variable IC50 values depending on cell type and assay conditions with typical IC50 ranges documented from 1-10 nM in receptor binding assays providing a reference concentration range for experimental designs
Apexbio Technology LLC Cortisone acetate 50-04-4 10mM (in 1mL DMSO)
Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
Medchemexpress LLC Hydrocortisone phosphate sodium | 6000-74-4 | MFCD00152562 | 99.1% | 486.40 g·mol⁻¹ | C21H29Na2O8P | 50 MG
Hydrocortisone phosphate sodium is the disodium phosphate salt of hydrocortisone, a water-soluble corticosteroid used as a research reagent. It has corticosteroid activity with relatively low anti-inflammatory potency and a short duration of action, and is used in biochemical and pharmacological studies, including research on ocular conditions and gastric ulcers.
- Water-soluble sodium phosphate salt suitable for aqueous formulations.
- Useful for biochemical and pharmacological research of corticosteroid activity.
- Relatively low anti-inflammatory potency with short duration of action.
- High purity and defined molecular weight for reproducible results.
- Stable when stored sealed and away from moisture; follow cold storage recommendations for solutions.
TARGETMOL CHEMICALS INC Hydrocortisone hemisuccinate
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent. Purity 98.8%
Medchemexpress LLC Hydrocortisone hemisuccinate (sodium) | 125-04-2 | 99.7% | 484.51 g/mol | C25H33NaO8 | 10 MG
Hydrocortisone hemisuccinate sodium is the sodium salt of hydrocortisone hemisuccinate, a steroidal glucocorticoid used as a research reagent. It is water-soluble and commonly used in anti-inflammatory and glucocorticoid receptor studies, including models of ulcerative colitis. For research use only; not for human consumption.
- High purity (99.66%) suitable for analytical and biological research.
- Water-soluble sodium salt for improved aqueous solubility.
- Reported molecular weight 484.51 g/mol and CAS 125-04-2.
- Available in small laboratory pack sizes, including 10 mg and solution formats.
- Datasheet and safety data sheet available for handling and assay information.
Medchemexpress LLC Hydrocortisone sodium phosphate | 6000-74-4 | MFCD00152562 | 99.1% | 486.40 g/mol | C21H29Na2O8P | 25 MG
Hydrocortisone sodium phosphate is the sodium phosphate ester of hydrocortisone, a water-soluble corticosteroid with glucocorticoid anti-inflammatory activity and a short duration of action. It is supplied as a solid research reagent for biochemical and pharmacological studies; consult the safety data sheet for handling and storage.
- Water-soluble sodium phosphate ester of hydrocortisone.
- Provides glucocorticoid anti-inflammatory activity with short duration of action.
- High reported purity supports analytical and biological experiments.
- Suitable for in vitro and in vivo research applications.
- Packaged as a 25 mg solid for convenient small-scale use.
Sigma Aldrich Fine Chemicals Biosciences Prednisone Impurity J Phar50MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Apexbio Technology LLC Prednisone 53-03-2 10mM (in 1mL DMSO)
Prednisone is a synthetic glucocorticoid which functions primarily as an agonist of the glucocorticoid receptor (GR) Upon binding to the GR prednisone induces receptor translocation into the nucleus initiating the regulation of gene expression involved in inflammation immune responses and cellular proliferation Due to its immunosuppressive mechanism prednisone is widely used as an experimental tool in biomedical studies exploring inflammatory diseases autoimmune conditions and immune signaling pathways Structurally prednisone is a corticosteroid derivative characterized by specific modifications that affect its pharmacodynamics and bioavailability In laboratory settings prednisone assists researchers in dissecting glucocorticoid-mediated physiological and molecular events evaluating receptor-ligand interactions and examining downstream signaling mechanisms in various cell-based assays and animal models
Medchemexpress LLC Dexamethasone | 50-02-2 | MFCD00064136 | C22H29FO5 | 10MG
Dexamethasone is a synthetic glucocorticoid receptor agonist provided as a GMP-grade small molecule for research and analytical applications. The GMP material is intended as an auxiliary reagent in regulated cell therapy workflows and is offered in small pack sizes for analytical or process development use.
- Agonist of the glucocorticoid receptor.
- Provided as GMP grade for use in regulated workflows.
- Intended as an auxiliary reagent for cell therapy manufacture.
- Available in small pack sizes suitable for analytical use.
- CAS number 50-02-2; molecular formula C22H29FO5.